Polynucleotides

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 Polynucleotides are a revolutionary treatment for skin and hair rejuvenation and regeneration, working at a deep cellular level to improve overall skin health and quality.

What Concerns Does it Address?

• Under-eye puffiness and dark circles

• Fine lines and skin laxity

• Loss of elasticity and firmness

• Dull or dehydrated skin

• Hair thinning and scalp health

At Base Skin Clinic, we use Plinest, an advanced polynucleotide treatment designed to restore a youthful glow and natural radiance from within. 

 Plinest uses patented Highly Purified Technology (HPT), making it one of the most refined and clinically advanced polynucleotide products available. Its exceptional purity ensures optimal safety, effectiveness and consistent results.

Derived from the building blocks of DNA, Plinest works by repairing and rejuvenating skin cells. It stimulates the skin’s natural repair processes, encouraging collagen and elastin production to improve skin structure, firmness and elasticity over time.

Prices

Under-eye    £220 (Course of 3 recommended £600)

Full face       £320 (course of 3 recommended £800)

Hands          £220 (course of 3 recommended £600)

Neck            £220 (Course of 3 recommended £600)

Décolletage £320 (course of 3 recommended £800)

Frequently Asked Questions

How many treatments will I need?

A course of 3 treatments, spaced 2-3  weeks apart, is recommended for optimal results. Maintenance sessions every 6–12 months help sustain results.

Is Plinest the same as Profhilo?

No. Polynucleotides work differently from Profhilo. Where Profhilo is a skin booster using hyaluronic acid, Plinest works at a cellular DNA level to repair and regenerate skin. The treatments complement each other but target different concerns.

Is it painful?

Discomfort is minimal. A fine needle is used and the treatment takes around 30 minutes. A topical anaesthetic will be applied.

When will I see results?

Skin quality improvements are typically visible after the second treatment, with the full benefit of a course appearing around 4–6 weeks after the final session.